Triamcinolone – Dosage, Indications, and Side Effects

medicine

What is Triamcinolone? Triamcinolone is an artificial glucocoticoid that is given by drinking, by injection or by sucking, or can also be used as a topical cream. The benefits of triamcinolone to treat allergies , skin conditions, ulcerative colitis and arthritis.

Name : Triamcinolone
Trade name : Kenalog IV, aristospan, trivaris
Class : Corticosteroids
Drugs that include corticosteroid classes : Betamethasone, corticotropin, cortisone, dexamethasone, hydrocortisone, methylprednisolone, prednisolone, prednisone, triamcinolone

Triamcinolone preparations

Injection suspension:

  • 5mg / mL
  • 10mg / mL
  • 20mg / mL
  • 40mg / mL

Triamcinolone acetonide

Treatment for rheumatic disorders or arthritis ( arthritis ):

  • 60 mg IM every 6 weeks; can be supplemented with an additional 20-100 mg IM PRN
  • Intralesi injection (10 mg / mL suspension): 1 mg per injection site 1 or more times a week; does not exceed 30 mg / day
  • Intra-articular / intrasynovial / soft tissue injection: large joints, 15-40 mg; small joint / tendon inflammation sheath, 2.5-10 mg

Triamcinolone Hexacetonide

Treatment for rheumatic disorders or arthritis (arthritis):

  • Injection Intralesi: 0.5 mg / ²; repeated if necessary
  • Intra-articular injection (20 mg / mL suspension): 10-20 mg (large joint); 2-6 mg (small joints); repeated every 3-4 weeks if necessary

 
Consideration of Triamcinolone Dosage

  • Dilute with local anesthesia (1% lidocaine or 2% without parabens) before intra-articular injection or intralesional injection
  • Dilute with D5 / NS or D10 / NS or NS or SWI before intralesional injection
  • Avoid diluents containing parabens or phenols

Triamcinolone Dosage and Indications for Children

Triamcinolone acetonide

Treatment of rheumatic conditions:

  • Dosage is 0.11 to 1.6 mg / kg / day IM divided every 3-4 hours
  • 6-12 years of age: 0.03-0.2 mg / kg IM every 1-7 days
  • Age> 12 years: 60 mg IM every 6 weeks; can be supplemented with an additional 20-100 mg IM PRN
  • Age> 12 years, intralesional injection (10 mg / mL suspension): 1 mg per injection site 1 or more times a week; does not exceed 30 mg / day

Triamcinolone Side Effects

Unknown frequency:

  • Acne
  • Arrhythmia
  • Enlargement of the heart
  • Circulation collapse
  • Adrenal suppression
  • Anaphylaxis
  • Vasculitis
  • Increased intracranial pressure
  • Thromboembolism
  • Euphoria
  • Arthragia
  • Stroke
  • Fracture / fracture
  • Damage to joint tissues
  • Lupus erythematosus lesions
  • Hypertrichosis
  • Cataract
  • Post wound healing
  • Diabetes mellitus
  • Epistaxis
  • Neuritis
  • Hirsutism
  • Appetite increases
  • Indigestion
  • Tendon rupture
  • Insomnia
  • Myopathy
  • Osteoporosis
  • Pseudotumor cerebri
  • Psychosis
  • Vertigo

Triamcinolone in Pregnancy and Breastfeeding

Safety for pregnancy: Category C

Types of drug categories for pregnancy:

  • Category A : Generally acceptable, has been through research in pregnant women, and shows no evidence of fetal damage
  • Category B : May be accepted by pregnant women, has been through research in experimental animals but there is no direct research evidence in humans
  • Category C : Use carefully. Research in experimental animals shows risk and there is no direct research in humans
  • Category D : Used if there are no other drugs that can be used, and in life-threatening conditions
  • Category X : Don’t use it in pregnancy
  • NA Category : No information

In nursing mothers, the triamcinolone drug can be excreted through breast milk, use it carefully.

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